Recurrent aphthous stomatitis (RAS) is a common condition, restricted to the mouth, and typically starts in childhood or adolescence as recurrent small, round or ovoid ulcers with circumscribed margins, erythematous haloes, and yellow or gray floors. RAS has three clinical types: minor, major and herpetiform ulcers. Ulcers with similar clinical features (aphthous-like ulcers) may be associated with systemic conditions such as Behçet syndrome, auto-inflammatory syndromes, gastrointestinal disease or immune defects such as HIV/AIDS.The etiology of recurrent aphthous stomatitis (RAS) is not entirely clear. A genetic basis exists for some RAS...
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